Assessment of Ki-67 and mitoses in pituitary neuroendocrine tumours-Consistency counts

Abstract

Pituitary neuroendocrine tumour Ki-67 proliferation index varies according to the number of tumour cells assessed. Consistent Ki-67 scoring approaches and re-evaluation of the recommended Ki-67 3% cut-off are required to clarify controversies in pituitary neuroendocrine tumour Ki-67 proliferation index assessment.

Keywords: Ki‐67; digital pathology; mitotic index; neuropathology; pituitary adenoma; pituitary neuroendocrine tumour.