Oligodendroglioma: a neurological perspective in Sub-saharan Africa

Neurosurg Rev. 2024 Jul 13;47(1):321. doi: 10.1007/s10143-024-02579-7.

Abstract

Gliomas are a kind of brain cancer that develops from glial cells. Glial cells provide nourishment and energy to nerve cells, and they also preserve the blood-brain barrier. A primary cancer of the central nervous system (CNS) is oligodendroglioma. This suggests that it originates in the brain or spinal cord. While oligodendrogliomas can strike anyone at any age, the age range of 35 to 44 is when they most commonly occur. Oligodendrogliomas are rare in young people and more common in men than women. Based on anecdotal data, patients with oligodendroglioma may present management challenges in Africa. There are delays in diagnosis and referrals due to the scarcity of neuroimaging facilities. A wide range of strategies have been put forth to improve pathology services in low- and middle-income nations. Adequate mentorship, short-term visitor programs, overcoming supply chain constraints, establishing training standards, and establishing the role of pathologists in cancer screening and early diagnosis have all been proposed as solutions to this problem. To sum up, oligodendroglioma is one of the low-grade gliomas this study looked at. Brain cancer is a serious public health concern in Africa. Improved options for screening and therapy are required to better address this problem.

Keywords: Cancer; Diagnosis; Gliomas; Oligodendroglioma; Tumor.

Publication types

  • Review
  • Letter

MeSH terms

  • Adult
  • Africa South of the Sahara / epidemiology
  • Brain Neoplasms* / diagnosis
  • Brain Neoplasms* / therapy
  • Female
  • Humans
  • Male
  • Oligodendroglioma* / diagnosis