Crystal structure and Hirshfeld surface analysis of 1-[6-bromo-2-(4-fluoro-phen-yl)-1,2,3,4-tetra-hydroquinolin-4-yl]pyrrolidin-2-one

Acta Crystallogr E Crystallogr Commun. 2024 Jun 25;80(Pt 7):777-782. doi: 10.1107/S2056989024005826. eCollection 2024 Jun 1.

Abstract

In the title compound, C19H18BrFN2O, the pyrrolidine ring adopts an envelope conformation. In the crystal, mol-ecules are linked by inter-molecular N-H⋯O, C-H⋯O, C-H⋯F and C-H⋯Br hydrogen bonds, forming a three-dimensional network. In addition, C-H⋯π inter-actions connect mol-ecules into ribbons along the b-axis direction, consolidating the mol-ecular packing. The inter-molecular inter-actions in the crystal structure were qu-anti-fied and analysed using Hirshfeld surface analysis.

Keywords: Hirshfeld surface analysis; acyl­ation; crystal structure; maleic acid amide; thienyl­allyl­amines; weak inter­actions.