PAK4-targeted PROTACs in clear cell renal cell carcinoma: a two-for-one targeted and immune therapy?

EBioMedicine. 2024 Jul:105:105218. doi: 10.1016/j.ebiom.2024.105218. Epub 2024 Jun 25.
No abstract available

Publication types

  • Letter

MeSH terms

  • Carcinoma, Renal Cell* / drug therapy
  • Carcinoma, Renal Cell* / metabolism
  • Carcinoma, Renal Cell* / pathology
  • Humans
  • Immunotherapy / methods
  • Kidney Neoplasms* / drug therapy
  • Kidney Neoplasms* / metabolism
  • Kidney Neoplasms* / pathology
  • Molecular Targeted Therapy*
  • Proteolysis Targeting Chimera
  • p21-Activated Kinases / antagonists & inhibitors
  • p21-Activated Kinases / genetics
  • p21-Activated Kinases / metabolism

Substances

  • p21-Activated Kinases
  • Proteolysis Targeting Chimera