Expert consensus on endodontic therapy for patients with systemic conditions

Xin Xu; Xin Zheng; Fei Lin; Qing Yu; Benxiang Hou; Zhi Chen; Xi Wei; Lihong Qiu; Chen Wenxia; Jiyao Li; Lili Chen; Zuomin Wang; Hongkun Wu; Zhiyue Lu; Jizhi Zhao; Yuhong Liang; Jin Zhao; Yihuai Pan; Shuang Pan; Xiaoyan Wang; Deqin Yang; Yanfang Ren; Lin Yue; Xuedong Zhou

doi:10.1038/s41368-024-00312-0

Expert consensus on endodontic therapy for patients with systemic conditions

Int J Oral Sci. 2024 Jun 17;16(1):45. doi: 10.1038/s41368-024-00312-0.

Authors

Xin Xu^#¹, Xin Zheng^#¹, Fei Lin^#², Qing Yu³, Benxiang Hou⁴, Zhi Chen⁵, Xi Wei⁶, Lihong Qiu⁷, Chen Wenxia⁸, Jiyao Li¹, Lili Chen⁹, Zuomin Wang¹⁰, Hongkun Wu¹¹, Zhiyue Lu¹², Jizhi Zhao¹³, Yuhong Liang¹⁴, Jin Zhao¹⁵, Yihuai Pan¹⁶, Shuang Pan¹⁷, Xiaoyan Wang², Deqin Yang^{18

19}, Yanfang Ren²⁰, Lin Yue²¹, Xuedong Zhou²²

Affiliations

¹ State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
² Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Peking University, Beijing, China.
³ State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, National Clinical Research Center for Oral Diseases, Shaanxi Key Laboratory of Oral Diseases, Department of Operative Dentistry & Endodontics, School of Stomatology, The Fourth Military Medical University, Xi'an, China.
⁴ Center for Microscope Enhanced Dentistry, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
⁵ State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
⁶ Department of Operative Dentistry and Endodontics, Hospital of Stomatology, Guanghua School of Stomatology, Sun Yat-Sen University & Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China.
⁷ Department of Endodontics, School of Stomatology, China Medical University, Shenyang, China.
⁸ College & Hospital of Stomatology, Guangxi Medical University, Nanning, China.
⁹ Department of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
¹⁰ Department of Stomatology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
¹¹ State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Department of Geriatric Dentistry, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
¹² Beijing Hospital, National Center of Gerontology, Beijing, China.
¹³ Department of Stomatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
¹⁴ Department of Emergency, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & NMPA Key Laboratory for Dental Materials, Beijing, China.
¹⁵ Department of Endodontics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.
¹⁶ Department of Endodontics, School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, China.
¹⁷ Department of Endodontics, The First Affiliated Hospital of Harbin Medical University & Department of Endodontics, School of Stomatology, Harbin Medical University, Harbin, China.
¹⁸ Department of Conservative Dentistry and Endodontics, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China.
¹⁹ Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China.
²⁰ Eastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA. yanfang_ren@urmc.rochester.edu.
²¹ Department of Cariology and Endodontology, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Peking University, Beijing, China. kqlinyue@bjmu.edu.cn.
²² State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China. zhouxd@scu.edu.cn.

^# Contributed equally.

Abstract

The overall health condition of patients significantly affects the diagnosis, treatment, and prognosis of endodontic diseases. A systemic consideration of the patient's overall health along with oral conditions holds the utmost importance in determining the necessity and feasibility of endodontic therapy, as well as selecting appropriate therapeutic approaches. This expert consensus is a collaborative effort by specialists from endodontics and clinical physicians across the nation based on the current clinical evidence, aiming to provide general guidance on clinical procedures, improve patient safety and enhance clinical outcomes of endodontic therapy in patients with compromised overall health.

Publication types

Review

MeSH terms

Consensus*
Dental Care for Chronically Ill
Dental Pulp Diseases / therapy
Humans
Root Canal Therapy*