[Interpretation of T-cell and NK-cell lymphoid proliferations and lymphomas in the 5th edition of the WHO classification of haematolymphoid tumours]

Zhonghua Bing Li Xue Za Zhi. 2024 Jun 8;53(6):535-540. doi: 10.3760/cma.j.cn112151-20230823-00094.
[Article in Chinese]

Abstract

The 5th edition of the World Health Organization (WHO) classification of haematolymphoid tumours used the hierarchical system to classify T-cell and NK-cell lymphoid proliferations and lymphomas (T/NK-LPD/LYM) based on research advances and clinicopathological characteristics of the diseases. In this edition of classification, tumour-like lesions were included, some tumors were added/deleted, the names or terms of certain diseases were refined, and the diagnostic criteria or subtypes of some diseases were revised. This group of diseases was reintegrated from non-clonal hyperplasia to highly aggressive lymphoma, which would further reflect the nature of T/NK-LPD/LYM and benefit to clinical application.

第5版WHO造血与淋巴组织肿瘤分类对T细胞和NK细胞增生性疾病和淋巴瘤(T-cell and NK-cell lymphoid proliferations and lymphomas,T/NK-LPD/LYM)根据研究进展以及疾病的临床病理特征,采用了分级系统进行分类。同时纳入了瘤样病变,引入/删除一些肿瘤,修改某些疾病的名称,并修订一些疾病的诊断标准或亚型,将这组疾病从非克隆性增生到高度侵袭性淋巴瘤进行了重新整合,更体现了T/NK-LPD/LYM的疾病本质,有利于临床应用。.

Publication types

  • English Abstract

MeSH terms

  • Humans
  • Killer Cells, Natural* / immunology
  • Killer Cells, Natural* / pathology
  • Lymphoma* / classification
  • Lymphoma* / immunology
  • Lymphoma* / pathology
  • Lymphoma, T-Cell / classification
  • Lymphoma, T-Cell / immunology
  • Lymphoma, T-Cell / pathology
  • Lymphoproliferative Disorders / classification
  • Lymphoproliferative Disorders / immunology
  • Lymphoproliferative Disorders / pathology
  • T-Lymphocytes* / immunology
  • T-Lymphocytes* / pathology
  • World Health Organization*