Patients with a cardiac complete response in AL amyloidosis have survival rates similar to those of a matched general population

Blood. 2024 Aug 15;144(7):790-793. doi: 10.1182/blood.2024024623.

Abstract

The survival of patients achieving a cardiac complete response in light chain amyloidosis, defined as N-terminal pro B-type natriuretic peptide ≤350 pg/mL or B-type natriuretic peptide ≤80 pg/mL, was similar to that of a matched general population, with estimated 5-year survival rates of 93% and 95%, respectively.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Amyloidosis* / mortality
  • Female
  • Humans
  • Immunoglobulin Light-chain Amyloidosis / drug therapy
  • Immunoglobulin Light-chain Amyloidosis / mortality
  • Male
  • Middle Aged
  • Natriuretic Peptide, Brain / blood
  • Peptide Fragments / blood
  • Survival Rate

Substances

  • Natriuretic Peptide, Brain
  • pro-brain natriuretic peptide (1-76)
  • Peptide Fragments