Intestinal T-cell lymphoma not otherwise specified: a case report and literature review

Future Sci OA. 2024 May 20;10(1):FSO942. doi: 10.2144/fsoa-2023-0119. eCollection 2024.

Abstract

Intestinal T-cell lymphoma, not otherwise specified (ITCL, NOS), primarily affects the small bowel but can involve the stomach and large bowel. This report presents an uncommon case of ITCL, NOS in a patient affecting the large bowel, supported by a literature review. An 87-year-old female presented with abdominal pain, fever, vomiting and weight loss. Imaging revealed nodular thickening of the transverse and right colon, confirmed as polypoid mass lesions with ulceration through colonoscopy and biopsy, indicating ITCL, NOS. CT scan showed adrenal nodes classifying it as stage VI. The patient was referred for palliative care and passed away 40 days later, likely due to tumor progression. This case underscores the rarity of large bowel ITCL, NOS and the diagnosis challenge.

Keywords: extranodal non-Hodgkin's lymphoma; intestinal T-cell lymphoma not otherwise specified; intestinal tumor.

Publication types

  • Case Reports