Takotsubo Syndrome After Pacemaker Implantation: A Case Report and Literature Review

J Innov Card Rhythm Manag. 2024 May 15;15(5):5852-5856. doi: 10.19102/icrm.2024.15051. eCollection 2024 May.

Abstract

A 78-year-old male patient with complete atrioventricular block underwent an uncomplicated pacemaker implantation. After 24 h, he presented acute chest pain, dyspnea, ST-segment-elevation in the anterior leads, left ventricular apical ballooning, and an ejection fraction of 35%. His coronary angiogram was normal. Within 2 days, his symptoms and electrocardiogram (ECG) abnormalities disappeared, while wall motion abnormalities recovered after 6 weeks. A diagnosis of takotsubo syndrome (TTS) was made. Pacemaker implantation has been described as a potential trigger for TTS. The clinical picture exhibits some peculiarities, including a higher percentage of men and asymptomatic patients and challenging ST-segment interpretation of paced ECGs. It is unclear whether pathophysiologic mechanisms are different compared to other forms of TTS and whether the acute initiation of ventricular pacing plays a role.

Keywords: CIED complications; pacemaker implantation; takotsubo syndrome.

Publication types

  • Case Reports