Extended distal femur resection: Megaprosthesis with telescopic bone allograft augmentation versus total femur prosthesis

J Surg Oncol. 2024 Jun;129(8):1568-1576. doi: 10.1002/jso.27670. Epub 2024 May 27.

Abstract

Background and objective: Oncological distal femur resections can leave a proximal femur too short to host a stem. Reconstructive techniques are then challenging. The purpose of the study is to compare implant survival, complication rate and MSTS of two different options.

Methods: We retrospectively divided 33 patients with primary bone tumours of distal femur in Group 1 (16 patients reconstructed with knee megaprosthesis with proximal bone augmentation, APC) and Group 2 (17 patients reconstructed with total femur prosthesis, TFP). Less than 12 cm of remaining proximal femur were planned for all resections.

Results: MSTS score at 2 years is 25 ± 5 for Group 1 and 19 ± 7 for Group 2 (confidence interval [C.I.] 95%, p = 0.02). At 5 years it is 27 ± 2 for Group 1 and 22 ± 6 for Group 2 (C.I. 95%, p = 0.047). Failure and complication rates are lower for Group 1, but no statistical significance was reached. In APC reconstruction, union at the host-allograft junction was achieved in 16 out of 16 patients using the telescopic bone augmentation technique.

Conclusions: APC provides higher functional results compared to TFP after extended distal femur resection. In APC reconstruction, telescopic augmentation is excellent for achieving union at the host-allograft junction.

Keywords: allograft prosthetic composite; bone allograft augment; knee megaprosthesis; malignant bone tumour; telescopic technique; total femur prosthesis.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Allografts
  • Bone Neoplasms / pathology
  • Bone Neoplasms / surgery
  • Bone Transplantation* / methods
  • Female
  • Femoral Neoplasms* / pathology
  • Femoral Neoplasms* / surgery
  • Femur* / surgery
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Plastic Surgery Procedures / methods
  • Retrospective Studies
  • Young Adult