Prevalence and characteristics of preoperative patients with depression

Br J Anaesth. 2024 Jul;133(1):77-85. doi: 10.1016/j.bja.2024.04.017. Epub 2024 May 22.

Abstract

Background: Within the perioperative period, depression-related diagnoses are associated with postoperative complications. We developed a perioperative depression screening programme to assess disease prevalence and feasibility for intervention.

Methods: Adult patients in multiple surgical departments at a single academic centre were screened for depression via the electronic health record patient portal or preoperative anaesthesia clinic before surgery, using the Patient Health Questionnaire (PHQ)-2 and -8. We utilised a broad method, screening all patients, and a focused method, only screening patients with a history of depression. Logistic regression was used to identify characteristics associated with clinically significant depression (PHQ-8 ≥10). Symptomatic patients were administered a brief psychoeducational intervention and referred for mental health services.

Results: A total of 3735 patients were identified by the broad and focused screens, of whom 2940 (79%) returned PHQ-2 data and were included in analysis. The broad screen (N=1216) found 46 (4%) patients who reported symptoms of moderate or greater severity. The focused screen (N=1724) found 242 (14%) patients with symptoms of moderate or greater severity and over all higher rates of depression across the symptom severity scale. Using the total screened pool, logistic regression identified a history of depression as the strongest associated patient characteristic variable but this did not capture most cases. Finally, we found that 66% of patients who were contacted about mental health services accepted referrals or sought outside care.

Conclusions: At least 4% of preoperative patients have clinically significant symptoms of depression, most of whom do not have a chart history of depression.

Keywords: Patient Health Questionnaire; depression; mental health services; perioperative; perioperative depression; preoperative depression screening; screening programme.

MeSH terms

  • Adult
  • Aged
  • Depression* / epidemiology
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Mass Screening / methods
  • Middle Aged
  • Postoperative Complications / epidemiology
  • Postoperative Complications / psychology
  • Preoperative Care* / methods
  • Preoperative Period
  • Prevalence