A 14;19 translocation in B-cell chronic lymphocytic leukemia: a new recurring chromosome aberration

Int J Cancer. 1985 Sep 15;36(3):287-90.

Abstract

Four of 30 patients with a diagnosis of B-CLL or prolymphocytic transformation of CLL, who had an adequate cytogenetic analysis, had abnormalities involving 14q32. Three of the 4 had a translocation involving chr. 19; in 2 of them it appeared to be t(14;19) (q32;q13.1). The third patient probably had the same translocation. All 3 patients had received therapy prior to cytogenetic analysis.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • B-Lymphocytes
  • Bone Marrow Cells
  • Chromosome Aberrations*
  • Chromosomes, Human, 13-15*
  • Chromosomes, Human, 19-20*
  • Humans
  • Karyotyping
  • Leukemia, Lymphoid / genetics*
  • Male
  • Translocation, Genetic*