Treatment of Francisella philomiragia bacteremia in a dog

J Vet Intern Med. 2024 Jul-Aug;38(4):2358-2361. doi: 10.1111/jvim.17104. Epub 2024 May 13.

Abstract

To describe the diagnosis and successful treatment of systemic francisellosis in a dog. An 11-year-old female spayed Labrador retriever presented for progressive lethargy, hyporexia, and cough. The dog was febrile with a neutrophilia, nonregenerative anemia, thrombocytopenia, and had increased activity in serum of liver-derived enzymes. Francisella philomiragia was isolated from aerobic blood culture. The dog was treated for 6 weeks with enrofloxacin orally. Repeated aerobic blood cultures after 2 and 6 weeks of antibiotic therapy were negative. The dog was clinically normal 7 months after diagnosis with no evidence of relapse.

Keywords: canine; fever; hepatopathy; infection; sepsis.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Anti-Bacterial Agents* / therapeutic use
  • Bacteremia* / drug therapy
  • Bacteremia* / microbiology
  • Bacteremia* / veterinary
  • Dog Diseases* / drug therapy
  • Dog Diseases* / microbiology
  • Dogs
  • Enrofloxacin* / therapeutic use
  • Female
  • Francisella*
  • Gram-Negative Bacterial Infections* / drug therapy
  • Gram-Negative Bacterial Infections* / microbiology
  • Gram-Negative Bacterial Infections* / veterinary

Substances

  • Enrofloxacin
  • Anti-Bacterial Agents