How far are we off? Analyzing the accuracy of surgical margin relocation in the head and neck

Head Neck. 2024 Nov;46(11):2709-2716. doi: 10.1002/hed.27793. Epub 2024 May 4.

Abstract

Background: Positive surgical margin rates remain high in head and neck cancer surgery. Relocation is challenging given the complex, three-dimensional (3D) anatomy.

Methods: Prospective, multi-institutional study to determine accuracy of head and neck surgeons and pathologists relocating margins on virtual 3D specimen models using written descriptions from pathology reports. Using 3D models of 10 head and neck surgical specimens, each participant relocated 20 mucosal margins (10 perpendicular, 10 shave).

Results: A total of 32 participants, 23 surgeons and 9 pathologists, marked 640 margins. Of the 320 marked perpendicular margins, 49.7% were greater than 1 centimeter from the true margin with a mean relocation error of 10.2 mm. Marked shave margins overlapped with the true margin a mean 54% of the time, with no overlap in 44 of 320 (13.8%) shave margins.

Conclusions: Surgical margin relocation is imprecise and challenging even for experienced surgeons and pathologists. New communication technologies are needed.

Keywords: head and neck cancer; margin relocation; re‐resection; surgical margins.

Publication types

  • Multicenter Study

MeSH terms

  • Female
  • Head and Neck Neoplasms* / pathology
  • Head and Neck Neoplasms* / surgery
  • Humans
  • Imaging, Three-Dimensional
  • Male
  • Margins of Excision*
  • Prospective Studies