Intrathoracic non-tuberculous mycobacteriosis with endobronchial lesion in a child aged 11 with HIV infection diagnosed by bronchoscopic biopsy, EBUS-TBNA and confocal laser endomicroscopy

Folia Med (Plovdiv). 2024 Apr 30;66(2):282-286. doi: 10.3897/folmed.66.e109225.

Abstract

The diagnosis of intrathoracic non-tuberculous mycobacteriosis (NTM) is challenging. We report a case of a pediatric pulmonary NTM with endobronchial lesion and lymphadenitis in a child with HIV infection diagnosed by bronchoscopic biopsy, EBUS-TBNA and probe-based confocal laser endomicroscopy (pCLE). The pCLE showed a large number of highly fluorescent cells and zones of density and disorganized elastin fibers at alveolar areas. A combination of diagnostic endoscopic procedures is required to establish the diagnosis of NTM.

Keywords: biopsy bronchoscopy child confocal laser endomicroscopy EBUS-TBNA endobronchial HIV-infection non-tuberculous mycobacteriosis optical biopsy.

Publication types

  • Case Reports

MeSH terms

  • Biopsy / methods
  • Bronchoscopy* / methods
  • Child
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration*
  • HIV Infections* / complications
  • HIV Infections* / pathology
  • Humans
  • Male
  • Microscopy, Confocal* / methods
  • Mycobacterium Infections, Nontuberculous* / diagnosis
  • Mycobacterium Infections, Nontuberculous* / pathology