Characterization of Mycoviruses in Armillaria ostoyae and A. cepistipes in the Czech Republic

Viruses. 2024 Apr 15;16(4):610. doi: 10.3390/v16040610.

Abstract

Members of the genus Armillaria are widespread forest pathogens against which effective protection has not yet been developed. Due to their longevity and the creation of large-scale cloning of Armillaria individuals, the use of mycoviruses as biocontrol agents (BCAs) against these pathogens could be an effective alternative. This work describes the detection and characterization of viruses in Armillaria spp. collected in the Czech Republic through the application of stranded total RNA sequencing. A total of five single-stranded RNA viruses were detected in Armillaria ostoyae and A. cepistipes, including viruses of the family Tymoviridae and four viruses belonging to the recently described "ambivirus" group with a circular ambisense genome arrangement. Both hammerhead (HHRz) and hairpin (HpRz) ribozymes were detected in all the ambiviricot sequences. Armillaria viruses were compared through phylogenetic analysis and confirmed their specific host by direct RT-PCR. One virus appears to infect both Armillaria species, suggesting the occurrence of interspecies transmission in nature.

Keywords: ambivirus; biological control; circular genetic elements; root rot; tymovirus; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Armillaria* / genetics
  • Armillaria* / virology
  • Czech Republic
  • Fungal Viruses* / classification
  • Fungal Viruses* / genetics
  • Fungal Viruses* / isolation & purification
  • Genome, Viral*
  • Phylogeny*
  • Plant Diseases / microbiology
  • Plant Diseases / virology
  • RNA Viruses / classification
  • RNA Viruses / genetics
  • RNA Viruses / isolation & purification
  • RNA, Viral* / genetics
  • Sequence Analysis, RNA

Substances

  • RNA, Viral

Grants and funding

This study was supported by the Ministry of Agriculture of the Czech Republic, project QK1920412 and University of South Bohemia, project GAJU 080/2022/Z.