Extramammary Paget Disease of Oral Mucosa: Case Report with Literature Review

Melad N Dababneh; Danielle M Bottalico; Keith M Schneider; Michelle Moh; Ivan J Stojanov

doi:10.1007/s12105-024-01638-1

Extramammary Paget Disease of Oral Mucosa: Case Report with Literature Review

Head Neck Pathol. 2024 Apr 24;18(1):33. doi: 10.1007/s12105-024-01638-1.

Authors

Melad N Dababneh¹, Danielle M Bottalico², Keith M Schneider^{3

4}, Michelle Moh¹, Ivan J Stojanov⁵

Affiliations

¹ Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA.
² Head and Neck Institute, Cleveland Clinic, Cleveland, OH, USA.
³ Private Practice, Mentor, OH, USA.
⁴ Department of Oral and Maxillofacial Surgery, Case Western Reserve University School of Dental Medicine, Cleveland, OH, USA.
⁵ Robert J. Tomsich Department of Pathology and Laboratory Medicine, Cleveland Clinic, Cleveland, OH, USA. stojani@ccf.org.

Abstract

Extramammary Paget disease (EPMD) of the oral mucosa is an unusual and extremely rare condition, with fewer than ten cases documented. Here, we report a case of EMPD extensively involving oral mucosa and underlying salivary ducts in a 72-year-old male and review published clinical, histologic, immunophenotypic, and prognostic features of this rare entity.

Keywords: Extramammary; Oral mucosa; Paget disease.

Publication types

Case Reports
Review

MeSH terms

Aged
Humans
Male
Mouth Mucosa* / pathology
Mouth Neoplasms* / pathology
Paget Disease, Extramammary* / pathology