T Cell Subsets and Immune Homeostasis

Chuyu Wu; Mei-Ling Jiang; Tao Pang; Cun-Jin Zhang

doi:10.1007/978-1-0716-3754-8_3

T Cell Subsets and Immune Homeostasis

Methods Mol Biol. 2024:2782:39-63. doi: 10.1007/978-1-0716-3754-8_3.

Authors

Chuyu Wu^{1

2}, Mei-Ling Jiang¹, Tao Pang², Cun-Jin Zhang¹

Affiliations

¹ Department of Neurology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, Sichuan, China.
² State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Screening, Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases, China Pharmaceutical University, Nanjing, China.

PMID: 38622391
DOI: 10.1007/978-1-0716-3754-8_3

Abstract

T cells are a heterogeneous group of cells that can be classified into different subtypes according to different classification methods. The body's immune system has a highly complex and effective regulatory network that allows for the relative stability of immune system function. Maintaining proper T cell homeostasis is essential for promoting protective immunity and limiting autoimmunity and tumor formation. Among the T cell family members, more and more T cell subsets have gradually been characterized. In this chapter, we summarize the functions of some key T cell subsets and their impact on immune homeostasis.

Keywords: Helper T cells; Immune homeostasis; T cell subset; T cells.

MeSH terms

Autoimmunity
Homeostasis
Humans
Neoplasms*
T-Lymphocyte Subsets
T-Lymphocytes, Regulatory*