Screening and diagnosis of primary aldosteronism. Consensus document of all the Spanish Societies involved in the management of primary aldosteronism

Endocrine. 2024 Jul;85(1):99-121. doi: 10.1007/s12020-024-03751-1. Epub 2024 Mar 6.

Abstract

Primary aldosteronism (PA) is the most frequent cause of secondary hypertension (HT), and is associated with a higher cardiometabolic risk than essential HT. However, PA remains underdiagnosed, probably due to several difficulties clinicians usually find in performing its diagnosis and subtype classification. The aim of this consensus is to provide practical recommendations focused on the prevalence and the diagnosis of PA and the clinical implications of aldosterone excess, from a multidisciplinary perspective, in a nominal group consensus approach by experts from the Spanish Society of Endocrinology and Nutrition (SEEN), Spanish Society of Cardiology (SEC), Spanish Society of Nephrology (SEN), Spanish Society of Internal Medicine (SEMI), Spanish Radiology Society (SERAM), Spanish Society of Vascular and Interventional Radiology (SERVEI), Spanish Society of Laboratory Medicine (SEQC(ML)), Spanish Society of Anatomic-Pathology, Spanish Association of Surgeons (AEC).

Keywords: Adrenal venous sampling; Aldosterone to renin ratio; Hypertension; Primary aldosteronism.

Publication types

  • Practice Guideline
  • Review

MeSH terms

  • Consensus
  • Humans
  • Hyperaldosteronism* / diagnosis
  • Hyperaldosteronism* / therapy
  • Hypertension / diagnosis
  • Hypertension / etiology
  • Hypertension / therapy
  • Mass Screening / methods
  • Mass Screening / standards
  • Societies, Medical
  • Spain / epidemiology