[Examination of Urinary Sediment in a Patient with Lupus-Like HIV-Associated Immune Complex Kidney Disease (HIVICK) - Case Report and Review of the Literature]

G Ital Nefrol. 2024 Feb 28;41(1):2024-vol1.
[Article in Italian]

Abstract

Renal involvement is very common in patients with HIV infection. The phenotype varies from the most frequently "collapsing" variant of focal and segmental glomerulosclerosis (FSGS) to "lupus-like HIV-immune complex kidney disease" (HIVICK). The latter is characterized by a histological picture that recalls lupus nephropathy. Through a clinical case, we underline the importance of urinary sediment analysis in patients with suspected glomerulopathy. Findings such as the characteristic cells that show the typical appearance of Herpes virus (HSV) infection or LE cells have significantly supported the diagnosis of HIVICK. In light of the present observations, we suggest systematically carrying out a cytological examination of the urinary sediment to confirm diagnostic hypotheses of rare pathologies.

Keywords: HIV; HIVICK; HSV; LE cells; cytology; urinary sediment.

Publication types

  • Review
  • Case Reports
  • English Abstract

MeSH terms

  • Antigen-Antibody Complex
  • Glomerulosclerosis, Focal Segmental* / pathology
  • HIV
  • HIV Infections* / complications
  • HIV Infections* / pathology
  • Humans
  • Kidney / pathology
  • Kidney Diseases* / pathology

Substances

  • Antigen-Antibody Complex