MXene-Embedded Porous Carbon-Based Cu2O Nanocomposites for Non-Enzymatic Glucose Sensors

Tami Selvi Gopal; Jaimson T James; Bharath Gunaseelan; Karthikeyan Ramesh; Vimala Raghavan; Christina Josephine Malathi A; K Amarnath; V Ganesh Kumar; Sofia Jennifer Rajasekaran; Saravanan Pandiaraj; Muthumareeswaran Mr; Sudhagar Pitchaimuthu; Chamil Abeykoon; Abdullah N Alodhayb; Andrews Nirmala Grace

doi:10.1021/acsomega.3c09659

MXene-Embedded Porous Carbon-Based Cu₂O Nanocomposites for Non-Enzymatic Glucose Sensors

ACS Omega. 2024 Feb 12;9(7):8448-8456. doi: 10.1021/acsomega.3c09659. eCollection 2024 Feb 20.

Authors

Tami Selvi Gopal¹, Jaimson T James¹, Bharath Gunaseelan¹, Karthikeyan Ramesh¹, Vimala Raghavan¹, Christina Josephine Malathi A², K Amarnath³, V Ganesh Kumar³, Sofia Jennifer Rajasekaran⁴, Saravanan Pandiaraj⁵, Muthumareeswaran Mr⁶, Sudhagar Pitchaimuthu⁷, Chamil Abeykoon⁸, Abdullah N Alodhayb⁹, Andrews Nirmala Grace¹

Affiliations

¹ Centre for Nanotechnology Research, Vellore Institute of Technology, Vellore, Tamil Nadu 632014, India.
² Department of Communication Engineering, School of Electronics Engineering (SENSE), Vellore Institute of Technology, Vellore, Tamil Nadu 632014, India.
³ Department of Chemistry and Centre for Ocean Research, Sathyabama Institute of Science and Technology, Chennai 600119, India.
⁴ Department of Physics, PPG Institute of Technology, Saravanampatti, Coimbatore 641034, India.
⁵ Department of Self-Development Skills, King Saud University, Riyadh 11451, Saudi Arabia.
⁶ College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
⁷ Research Centre for Carbon Solutions, Institute of Mechanical, Processing and Energy Engineering, School of Engineering & Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS, U.K.
⁸ Northwest Composites Centre, Aerospace Research Institute, and Department of Materials, Faculty of Science and Engineering, The University of Manchester, Oxford Road, Manchester M13 9PL, U.K.
⁹ Department of Physics and Astronomy, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.

Abstract

This work explores the use of MXene-embedded porous carbon-based Cu₂O nanocomposite (Cu₂O/M/AC) as a sensing material for the electrochemical sensing of glucose. The composite was prepared using the coprecipitation method and further analyzed for its morphological and structural characteristics. The highly porous scaffold of activated (porous) carbon facilitated the incorporation of MXene and copper oxide inside the pores and also acted as a medium for charge transfer. In the Cu₂O/M/AC composite, MXene and Cu₂O influence the sensing parameters, which were confirmed using electrochemical techniques such as cyclic voltammetry, electrochemical impedance spectroscopy, and amperometric analysis. The prepared composite shows two sets of linear ranges for glucose with a limit of detection (LOD) of 1.96 μM. The linear range was found to be 0.004 to 13.3 mM and 15.3 to 28.4 mM, with sensitivity values of 430.3 and 240.5 μA mM^-1 cm^-2, respectively. These materials suggest that the prepared Cu₂O/M/AC nanocomposite can be utilized as a sensing material for non-enzymatic glucose sensors.