One nucleotide substitution in the 3'UTR generated the novel allele HLA-B*40:01:02:47 in a North Indian individual

HLA. 2024 Feb;103(2):e15377. doi: 10.1111/tan.15377.

Authors

Akanksha Sharma¹, Soumita Bagchi², Adarsh W Barwad³, Sanjay Kumar Agarwal², Uma Kanga¹

Affiliations

¹ Department of Transplant Immunology and Immunogenetics, Clinical Immunogenetics Laboratory, Centre for Excellence in Molecular Medicine (ICMR), All India Institute of Medical Sciences, New Delhi, India.
² Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
³ Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

PMID: 38342777
DOI: 10.1111/tan.15377

Abstract

HLA-B*40:01:02:47 differs from HLA-B*40:01:02:01 by one nucleotide change in the 3'UTR at position 2739 (A>T).

Keywords: HLA-B; North India; next generation sequencing; novel allele.

© 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

3' Untranslated Regions
Alleles
Genes, MHC Class I
HLA-B Antigens* / genetics
High-Throughput Nucleotide Sequencing
Humans
Nucleotides*

Substances

3' Untranslated Regions
Nucleotides
HLA-B Antigens

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