Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions
Nat Microbiol
.
2024 Jan;9(1):1-3.
doi: 10.1038/s41564-023-01566-w.
Authors
Julie Sollier
1
,
Marek Basler
1
,
Petr Broz
2
,
Petra S Dittrich
3
,
Knut Drescher
1
,
Adrian Egli
4
,
Alexander Harms
5
,
Andreas Hierlemann
3
,
Sebastian Hiller
1
,
Carolyn G King
6
,
John D McKinney
7
,
Jacob Moran-Gilad
8
,
Richard A Neher
1
,
Malcolm G P Page
9
,
Sven Panke
3
,
Alexandre Persat
7
,
Paola Picotti
10
,
Katharina M Rentsch
11
,
Pablo Rivera-Fuentes
12
,
Uwe Sauer
10
,
Daiana Stolz
13
14
,
Sarah Tschudin-Sutter
15
16
,
Christian van Delden
17
,
Erik van Nimwegen
1
,
Jan-Willem Veening
18
,
Mattia Zampieri
6
,
Annelies S Zinkernagel
19
,
Nina Khanna
6
15
16
,
Dirk Bumann
1
,
Urs Jenal
1
,
Christoph Dehio
20
Affiliations
1
Biozentrum, University of Basel, Basel, Switzerland.
2
Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
3
Department of Biosystems Science and Engineering, ETH Zurich, Basel, Switzerland.
4
Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland.
5
Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
6
Department of Biomedicine, University Basel, Basel, Switzerland.
7
School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
8
Department of Health Policy and Management, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
9
Malcolm Page GmbH, Basel, Switzerland.
10
Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland.
11
Laboratory Medicine, University Hospital Basel, Basel, Switzerland.
12
Department of Chemistry, University of Zurich, Zurich, Switzerland.
13
Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital Basel, Basel, Switzerland.
14
Department of Pneumology, University Medical Center, Freiburg, Germany.
15
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland.
16
Department of Clinical Research, University Hospital Basel, Basel, Switzerland.
17
University Hospitals Geneva, Geneva, Switzerland.
18
Department of Fundamental Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
19
Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
20
Biozentrum, University of Basel, Basel, Switzerland. christoph.dehio@unibas.ch.
PMID:
38177300
DOI:
10.1038/s41564-023-01566-w
No abstract available
MeSH terms
Anti-Bacterial Agents* / pharmacology
Drug Discovery*
Humans
Substances
Anti-Bacterial Agents