Personalized dietary management of advanced prostate cancer using nutrigenomics: a case report

Eur J Clin Nutr. 2024 Apr;78(4):356-359. doi: 10.1038/s41430-023-01377-6. Epub 2023 Dec 9.

Abstract

While there are emerging reports in the scientific literature on potential associations between cholesterol/lipids and prostate cancer, information on the dietary management of these cancer patients is currently lacking. We report on a 57-year-old white Australian male diagnosed with advanced prostate cancer who had personalized dietary management in preparation for and following his medical treatment: radiation and radical prostatectomy. Dietary recommendations were based on his blood results and nutrigenomic tests which showed a history of and genetic predisposition to dyslipidemia. Nutritional analysis also confirmed the need for dietary modification of his fat intake. Eighteen months post medical and dietary intervention his PSA level was reported at 0.1 ug/L and all blood lipid levels were within reference ranges. At two years there was no detectable disease recurrence and androgen deprivation therapy (ADT) was not required. Personalized dietary recommendations could be a clinically beneficial addition to the multidisciplinary management of prostate cancer patients.

Publication types

  • Case Reports

MeSH terms

  • Androgen Antagonists
  • Australia
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Recurrence, Local / therapy
  • Nutrigenomics
  • Prostate-Specific Antigen
  • Prostatic Neoplasms* / genetics
  • Prostatic Neoplasms* / therapy

Substances

  • Prostate-Specific Antigen
  • Androgen Antagonists