No relationship between socioeconomic status, education level and development and progression of diabetic retinopathy in type 2 diabetes: a FIELD trial substudy

Ben Rao; Andrzej S Januszewski; Laima Brazionis; Rachel O'Connell; Nanda Aryal; Georgia Shimmin; Justin O'Day; Paul Mitchell; Peter G Colman; Anthony C Keech; Alicia J Jenkins; FIELD trial investigators

doi:10.1111/imj.16270

No relationship between socioeconomic status, education level and development and progression of diabetic retinopathy in type 2 diabetes: a FIELD trial substudy

Intern Med J. 2023 Nov;53(11):2128-2131. doi: 10.1111/imj.16270.

Authors

Ben Rao^{1

2}, Andrzej S Januszewski^{1

3

4}, Laima Brazionis⁴, Rachel O'Connell¹, Nanda Aryal⁵, Georgia Shimmin^{1

6}, Justin O'Day⁷, Paul Mitchell⁸, Peter G Colman^{4

9}, Anthony C Keech¹, Alicia J Jenkins^{1

2

10}; FIELD trial investigators

Affiliations

¹ NHMRC Clinical Trials Centre, The University of Sydney, Sydney, New South Wales, Australia.
² Faculty of Medicine, Monash University, Melbourne, Victoria, Australia.
³ Sydney Pharmacy School, The University of Sydney, Sydney, New South Wales, Australia.
⁴ Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia.
⁵ Australian Institute of Health Innovation, Macquarie University, Sydney, New South Wales, Australia.
⁶ Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
⁷ Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, The University of Melbourne, Melbourne, Victoria, Australia.
⁸ The Westmead Institute for Medical Research, Sydney, New South Wales, Australia.
⁹ Royal Melbourne Hospital, Melbourne, Victoria, Australia.
¹⁰ Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia.

PMID: 37997276
DOI: 10.1111/imj.16270

Abstract

In 6002 Australian adults with type 2 diabetes and a median 5-year follow-up in the FIELD (Fenofibrate Intervention and Event Lowering in Diabetes) trial, baseline socioeconomic status (SES) and self-reported education level were not related to development of on-trial sight-threatening diabetic retinopathy. Similarly, in a retinal photography substudy (n = 549), two-step diabetic retinopathy progression was not related to SES or education.

Keywords: fenofibrate; retinopathy; socioeconomic status; type 2 diabetes.

MeSH terms

Adult
Australia / epidemiology
Diabetes Mellitus, Type 2* / complications
Diabetes Mellitus, Type 2* / epidemiology
Diabetic Retinopathy* / epidemiology
Educational Status
Fenofibrate*
Humans

Substances

Fenofibrate

Grants and funding

1150467/National Health and Medical Research Council, Program Grant