Molecular detection of a translocation (Y;15) in a 45,X male

Hum Genet. 1986 Dec;74(4):372-7. doi: 10.1007/BF00280488.

Abstract

A 45,X male individual was shown to have a translocation of Y-chromosome material to the short arm or proximal long arm of chromosome 15. This translocation was detected by genomic DNA blotting and in situ hybridization with Y-chromosome-specific DNA probes.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Chromosome Banding
  • Chromosomes, Human, Pair 15*
  • DNA / genetics
  • Humans
  • Infant, Newborn
  • Karyotyping
  • Male
  • Noonan Syndrome / genetics*
  • Nucleic Acid Hybridization
  • Translocation, Genetic*
  • Y Chromosome*

Substances

  • DNA