1 Department of Neurology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7025, USA. Electronic address: howardj@neurology.unc.edu.
2 UCB Pharma, Monheim, Germany.
3 Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
4 Department of Neurology, Hanamaki General Hospital, Hanamaki, Japan.