Dental Considerations and Precautions Associated with Oral Excisional Biopsy on a Patient with Cushing's Syndrome (Hypercortisolism)

Sahar Mirfarsi; Dalia Seleem; Airani Sathananthan

doi:10.1016/j.cden.2023.05.005

Dental Considerations and Precautions Associated with Oral Excisional Biopsy on a Patient with Cushing's Syndrome (Hypercortisolism)

Dent Clin North Am. 2023 Oct;67(4):581-584. doi: 10.1016/j.cden.2023.05.005. Epub 2023 Jul 3.

Authors

Sahar Mirfarsi¹, Dalia Seleem², Airani Sathananthan³

Affiliations

¹ Western University of Health Sciences, College of Dental Medicine, 309 E. 2nd Street, Pomona, CA 91766, USA. Electronic address: Sahar.mirfarsi@westernu.edu.
² Western University of Health Sciences, College of Dental Medicine, 309 E. 2nd Street, Pomona, CA 91766, USA.
³ Western Universit of Health Sciences, Department of Internal Medicine, 795 E 2nd Street, Pomona, CA 91766, USA.

PMID: 37714599
DOI: 10.1016/j.cden.2023.05.005

Abstract

Chronic exposure to endogenous and exogenous glucocorticoids will cause CS. Endogenous CS is uncommon, with an annual incidence of 0.2-5 individuals per million. Endogenous causes could be 1. adrenocorticotropic hormone (ACTH) dependent or 2. ACTH independent. The use of exogenous glucocorticoids to manage chronic autoimmune or inflammatory diseases is the most common cause of CS and results in iatrogenic CS. Cushing disease is caused by excess ACTH production by a pituitary tumor. CS's clinical manifestations in the head and neck region include a moon-shaped face, acne flares, and hirsutism.

Keywords: Adrenal crisis; Corticosteroids; Cushing’s syndrome; Endocrine disease; Hypercortisolism.

Publication types

Review

MeSH terms

Adrenocorticotropic Hormone
Biopsy
Cushing Syndrome* / complications
Glucocorticoids
Humans

Substances

Glucocorticoids
Adrenocorticotropic Hormone