Sleep Disorders in Childhood

Continuum (Minneap Minn). 2023 Aug 1;29(4):1205-1233. doi: 10.1212/CON.0000000000001285.

Abstract

Objective: This article provides a comprehensive review of pediatric sleep disorders including the clinical features, diagnosis, and treatment of sleep-disordered breathing, insomnia, parasomnias, restless sleep disorder, restless legs syndrome, narcolepsy in childhood, and Kleine-Levin syndrome.

Latest developments: Our understanding of pediatric sleep pathophysiology continues to evolve, and diagnostic and treatment modalities have expanded. A low-sodium oxybate formulation was approved in July 2020 in the United States to treat cataplexy and excessive daytime sleepiness in patients 7 years old and older with narcolepsy. A validated pediatric hypersomnolence survey for pediatric narcolepsy and idiopathic hypersomnia with high sensitivity, specificity, and interrater reliability is now available.

Essential points: The clinical presentation, diagnostics, and treatment of children with sleep disorders differ from those of adults. Untreated sleep disorders in childhood can lead to adverse physical and psychological consequences in adults. Correctly diagnosing and treating sleep disorders in youth can prevent a significant burden of disease in adulthood.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Cataplexy*
  • Child
  • Disorders of Excessive Somnolence* / diagnosis
  • Disorders of Excessive Somnolence* / therapy
  • Humans
  • Narcolepsy* / diagnosis
  • Narcolepsy* / therapy
  • Parasomnias* / diagnosis
  • Parasomnias* / therapy
  • Reproducibility of Results
  • Sodium Oxybate*

Substances

  • Sodium Oxybate

Supplementary concepts

  • restless sleep disorder