The Potential Role of Torsemide in Optimizing Loop Diuretic Therapy for Heart Failure Patients

Cureus. 2023 Jul 16;15(7):e41957. doi: 10.7759/cureus.41957. eCollection 2023 Jul.

Abstract

Heart failure is associated with an increased frequency of hospitalization, reduced life span, and greater risk to public health, thus posing a challenge. In India, torsemide is one of the commonly used loop diuretics for decongestion in heart failure. However, this use of torsemide, including its dosing, and up/down titration, is based on practical experience. Loop diuretic therapy for heart failure patients poses several dilemmas due to the lack of robust evidence based on which treatment decisions can be made. To guide physicians on the optimal use of torsemide in heart failure patients with or without renal impairment, a panel of expert cardiologists and nephrologists from India convened to develop this expert opinion document for the use of torsemide. This expert opinion on torsemide will pave the way for optimal management with loop diuretic therapy in real-world heart failure patients.

Keywords: expert opinion; heart failure; loop diuretics; optimal management; torsemide.

Publication types

  • Review

Grants and funding

Nitin Zalte, Amarnath Sugumaran, and Senthilnathan Mohanasundaram are employees of Cipla Ltd.