Mucin-binding adhesins: A key to unlocking the door of mutualism

Geongoo Han; Shipra Vaishnava

doi:10.1016/j.chom.2023.07.007

Mucin-binding adhesins: A key to unlocking the door of mutualism

Cell Host Microbe. 2023 Aug 9;31(8):1254-1256. doi: 10.1016/j.chom.2023.07.007.

Authors

Geongoo Han¹, Shipra Vaishnava²

Affiliations

¹ Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA.
² Molecular Microbiology and Immunology, Brown University, Providence, RI 02912, USA. Electronic address: shipra_vaishnava@brown.edu.

PMID: 37562359
DOI: 10.1016/j.chom.2023.07.007

Abstract

From corals to mammals, mucus is a conserved feature that prevents microbes from accessing the surfaces that produce it. However, interactions between mucus and microbes remain poorly understood. In this issue of Cell Host & Microbe, Smith et al. unveil that mucus binding by bacteria is crucial for host-microbe symbiosis.

MeSH terms

Adhesins, Bacterial / metabolism
Animals
Bacteria / metabolism
Mammals
Mucins* / metabolism
Mucus / metabolism
Symbiosis*

Substances

Mucins
Adhesins, Bacterial