Periprosthetic Joint Infection: Current Clinical Challenges

Clin Infect Dis. 2023 Oct 5;77(7):e34-e45. doi: 10.1093/cid/ciad360.

Abstract

Over the last several decades, periprosthetic joint infection has been increasing in incidence and is occurring in more complex patients. While there have been advances in both surgical and medical treatment strategies, there remain important gaps in our understanding. Here, we share our current approaches to the diagnosis and management of periprosthetic joint infection, focusing on frequent clinical challenges and collaborative interdisciplinary care.

Keywords: antimicrobial treatment; periprosthetic joint infection; revision arthroplasty; rifampin; total joint arthroplasty.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Arthritis, Infectious* / diagnosis
  • Arthritis, Infectious* / drug therapy
  • Humans
  • Incidence
  • Prosthesis-Related Infections* / diagnosis
  • Prosthesis-Related Infections* / drug therapy
  • Prosthesis-Related Infections* / epidemiology
  • Reoperation / adverse effects