When Cancer and Cardiovascular Disease Intersect: The Challenge and the Opportunity of Cardio-Oncology

Aaron L Sverdlov; Bogda Koczwara; Daniel A Cehic; Robyn A Clark; Lee Hunt; Stephen J Nicholls; Liza Thomas; Elysia Thornton-Benko; Leonard Kritharides; Clinical Oncology Society of Australia (COSA)–Cardiac Society of Australia and New Zealand (CSANZ) Cardio-Oncology Working Group

doi:10.1016/j.hlc.2023.04.301

When Cancer and Cardiovascular Disease Intersect: The Challenge and the Opportunity of Cardio-Oncology

Heart Lung Circ. 2024 May;33(5):558-563. doi: 10.1016/j.hlc.2023.04.301. Epub 2023 Jun 14.

Authors

Aaron L Sverdlov¹, Bogda Koczwara², Daniel A Cehic³, Robyn A Clark⁴, Lee Hunt⁵, Stephen J Nicholls⁶, Liza Thomas⁷, Elysia Thornton-Benko⁸, Leonard Kritharides⁹; Clinical Oncology Society of Australia (COSA)–Cardiac Society of Australia and New Zealand (CSANZ) Cardio-Oncology Working Group

Affiliations

¹ Cardiovascular Department, John Hunter Hospital, Newcastle, NSW, Australia; Newcastle Centre of Excellence in Cardio-Oncology, Hunter Medical Research Institute, Hunter New England Local Health District, The University of Newcastle and Calvary Mater Newcastle, Newcastle, NSW, Australia. Electronic address: aaron.sverdlov@newcastle.edu.au.
² Department of Medical Oncology, Flinders Medical Centre, Adelaide, SA, Australia; Flinders Health and Medical Research Institute, Flinders University, Adelaide, SA, Australia.
³ Advara HeartCare, Adelaide, SA, Australia; School of Medicine, University of Adelaide, Adelaide, SA, Australia.
⁴ Caring Futures Institute, Flinders University, Adelaide, SA, Australia; Southern Adelaide Local Health Network (SALHN), Adelaide, SA, Australia.
⁵ Liverpool and Macarthur Cancer Therapy Centres, Sydney, NSW, Australia; South West Sydney Clinical School, UNSW Medicine, University of New South Wales, Sydney, NSW, Australia.
⁶ Monash Heart, Monash Health, Melbourne, Vic, Australia; Victorian Heart Institute, Monash University, Melbourne, Vic, Australia.
⁷ Cancer Voices NSW, Sydney, NSW, Australia; South West Sydney Clinical School, UNSW Medicine, University of New South Wales, Sydney, NSW, Australia; Department of Cardiology, Westmead Hospital, Sydney, NSW, Australia; Westmead Clinical School, The University of Sydney, Sydney, NSW, Australia.
⁸ Bondi Road Doctors, Sydney, NSW, Australia; School of Clinical Medicine, Faculty of Medicine and Health, The Behavioural Sciences Unit, University of New South Wales, Sydney, NSW, Australia; Kids Cancer Centre, Sydney Children's Hospital, Sydney, NSW, Australia.
⁹ Department of Cardiology, Concord Repatriation General Hospital, Sydney, NSW, Australia; ANZAC Medical Research Institute, Faculty of Medicine, The University of Sydney, Sydney, NSW, Australia.

PMID: 37321867
DOI: 10.1016/j.hlc.2023.04.301

Abstract

Cancer and cardiovascular disease (CVD) commonly coexist, with increasing evidence that long-term cancer survivors are more likely to die from CVD than the general population. Effective management of CVD and its risk factors requires identification of patients at increased risk who may benefit from early intervention and their appropriate monitoring across the disease trajectory. Improving outcomes requires new models of multidisciplinary cancer care supported by care pathways. Such pathways require a clear delineation of the roles and responsibilities of all team members and provision of appropriate enablers for their delivery. These include accessible point-of-care tools/risk calculators, patient resources, and the provision of tailored training opportunities for health care providers.

Keywords: Cardio-oncology; Challenges; Guidelines; Models of care.

Publication types

Review

MeSH terms

Cardio-Oncology
Cardiology
Cardiovascular Diseases* / etiology
Cardiovascular Diseases* / therapy
Humans
Medical Oncology* / methods
Neoplasms* / complications
Neoplasms* / therapy
Risk Factors