Neuropathologists play a key role in establishing the extent of COVID-19 in human patients

Lokman Cevik; Michele Joana Alves; José Javier Otero

doi:10.17879/freeneuropathology-2020-2736

Neuropathologists play a key role in establishing the extent of COVID-19 in human patients

Free Neuropathol. 2020 Apr 2:1:1-11. doi: 10.17879/freeneuropathology-2020-2736. eCollection 2020 Jan.

Authors

Lokman Cevik¹, Michele Joana Alves¹, José Javier Otero¹

Affiliation

¹ Div. of Neuropathology, Dept. of Pathology, The Ohio State University School of Medicine, Columbus, OH, USA.

PMID: 37283681
PMCID: PMC10209904
DOI: 10.17879/freeneuropathology-2020-2736

Abstract

SARS-CoV2 infection causes COVID-19, and represents the most emergent health care crisis of our generation. Ample evidence in the scientific literature suggests that SARS-CoV, MERS-CoV, and endemic human coronaviruses infect brain cells. We delineate a rationale for encouraging evaluation of the brain, and in particular the brainstem, in COVID-19 so that potential neuropathological mechanisms can be delineated.

Keywords: COVID-19; SARS-CoV2.