Which strain of the avian coronavirus vaccine will become the prevalent one in China next?

Haizhu Li; Gengsong Liu; Qiaoyan Zhou; Hongchun Yang; Congcong Zhou; Weili Kong; Jieyu Su; Gonghe Li; Hongbin Si; Changbo Ou

doi:10.3389/fvets.2023.1139089

Which strain of the avian coronavirus vaccine will become the prevalent one in China next?

Front Vet Sci. 2023 May 5:10:1139089. doi: 10.3389/fvets.2023.1139089. eCollection 2023.

Authors

Haizhu Li¹, Gengsong Liu¹, Qiaoyan Zhou¹, Hongchun Yang¹, Congcong Zhou¹, Weili Kong², Jieyu Su^{1

3

4}, Gonghe Li^{1

3

4}, Hongbin Si^{1

3

4}, Changbo Ou^{1

3

4}

Affiliations

¹ College of Animal Science and Technology, Guangxi University, Nanning, China.
² Gladstone Institute of Virology, University of California, San Francisco, San Francisco, CA, United States.
³ Guangxi Zhuang Autonomous Region Engineering Research Center of Veterinary Biologics, Nanning, China.
⁴ Guangxi Key Laboratory of Animal Reproduction, Breeding and Disease Control, Nanning, China.

Abstract

Infectious bronchitis virus (IBV) is a vital pathogen in poultry farms, which can induce respiratory, nephropathogenic, oviduct, proventriculus, and intestinal diseases. Based on the phylogenetic classification of the full-length S1 gene, IBV isolates have been categorized into nine genotypes comprising 38 lineages. GI (GI-1, GI-2, GI-3, GI-4, GI-5, GI-6, GI-7, GI-13, GI-16, GI-18, GI-19, GI-22, GI-28, and GI-29), GVI-1 and GVII-1 have been reported in China in the past 60 years. In this review, a brief history of IBV in China is described, and the current epidemic strains and licensed IBV vaccine strains, as well as IBV prevention and control strategies, are highlighted. In addition, this article presents unique viewpoints and recommendations for a more effective management of IBV. The recombinant Newcastle Disease virus (NDV) vector vaccine expressed S gene of IBV QX-like and 4/91 strains may be the dominant vaccine strains against NDV and IBV.

Keywords: Newcastle disease virus; S1 gene; coronavirus; genotype; infectious bronchitis virus; vaccine strain; vector vaccine.

Publication types

Review