Chronic frontal neurobehavioural symptoms in combat-deployed military personnel with and without a history of blast-related mild traumatic brain injury

Brain Inj. 2023 Aug 24;37(10):1127-1134. doi: 10.1080/02699052.2023.2209740. Epub 2023 May 11.

Abstract

Objective: This study evaluated frontal behavioural symptoms, via the FrSBe self-report, in military personnel with and without a history of blast-related mild traumatic brain injury (mild TBI).

Methods: Prospective observational cohort study of combat-deployed service members leveraging 1-year and 5-year demographic and follow up clinical outcome data.

Results: The blast mild TBI group (n = 164) showed greater frontal behavioural symptoms, including clinically elevated apathy, disinhibition, and executive dysfunction, during a 5-year follow-up, compared to a group of combat-deployed controls (n = 107) without mild TBI history or history of blast exposure. We also explored changes inbehaviourall symptoms over a 4-year span, which showed clinically significant increases in disinhibition in the blast mild TBI group, whereas the control group did not show significant increases in symptoms over time.

Conclusion: Our findings add to the growing evidence that a proportion of individuals who sustain mild TBI experience persistent behavioural symptoms. We also offer a demonstration of a novel use of the FrSBe as a tool for longitudinal symptom monitoring in a military mild TBI population.

Keywords: Mild traumatic brain injury; executive function; frontal behavioural symptoms; long term outcomes; military service members.

Publication types

  • Observational Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Blast Injuries*
  • Brain Concussion*
  • Explosions
  • Humans
  • Military Personnel*
  • Prospective Studies
  • Stress Disorders, Post-Traumatic* / epidemiology