Unilateral Multiple Extramedullary Plasmacytoma of the Choroid and Conjunctiva: A Case Report

Shymaa Mohamed; Truman Silvasi; Anthony Kubat; Thomas Aaberg Jr

doi:10.1177/2474126419893175

Unilateral Multiple Extramedullary Plasmacytoma of the Choroid and Conjunctiva: A Case Report

J Vitreoretin Dis. 2019 Dec 20;4(2):152-156. doi: 10.1177/2474126419893175. eCollection 2020 Mar-Apr.

Authors

Shymaa Mohamed¹, Truman Silvasi², Anthony Kubat³, Thomas Aaberg Jr¹

Affiliations

¹ Department of Ophthalmology, Foundation for Vision Research, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.
² Department of Ophthalmology, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA.
³ Michigan Pathology Specialists, Spectrum Health, Department of Pathology, Grand Rapids, MI, USA.

Abstract

Purpose: We report a case of multiple extramedullary plasmacytoma (EMP) of the choroid and conjunctiva as a sign of multiple myeloma (MM) relapse.

Methods: An observational case report with clinicopathologic correlation is presented.

Results: A 45-year-old man with a 2.5-year history of MM presented with left eye pain. Examination revealed a conjunctival nodule and choroidal infiltrate in the left eye. Excisional biopsy demonstrated plasmacytoma of the conjunctiva and choroid. Despite radiotherapy and chemotherapy, multiple EMP recurred and the patient died 8 months after initial presentation.

Conclusions: Multiple EMP of the choroid and conjunctiva has a poor prognosis and can present as a sign of MM relapse. Our imaging demonstrates the clinical manifestations of this tumor and can aid future diagnoses. Our radiation dose (20 Gy) was inadequate, which is an important reportable factor for future patients.

Keywords: choroid; conjunctiva; extramedullary; multiple; myeloma; plasmacytoma.

Publication types

Case Reports