PROMIS: Physical, Mental and Social Health Outcomes Improve From Before to Early After LVAD Implant: Findings From the Mechanical Circulatory Support: Measures of Adjustment and Quality of Life (MCS A-QOL) Study

Elizabeth A Hahn; Larry A Allen; Christopher S Lee; Quin E Denfeld; Josef Stehlik; David Cella; Joann Lindenfeld; Jeffrey J Teuteberg; Colleen K McIlvennan; Michael S Kiernan; David G Beiser; Mary N Walsh; Eric D Adler; Bernice Ruo; James K Kirklin; Liviu Klein; Katy Bedjeti; Peter D Cummings; James L Burns; Alyssa M Vela; Kathleen L Grady

doi:10.1016/j.cardfail.2023.03.013

PROMIS: Physical, Mental and Social Health Outcomes Improve From Before to Early After LVAD Implant: Findings From the Mechanical Circulatory Support: Measures of Adjustment and Quality of Life (MCS A-QOL) Study

J Card Fail. 2023 Oct;29(10):1398-1411. doi: 10.1016/j.cardfail.2023.03.013. Epub 2023 Mar 31.

Authors

Elizabeth A Hahn¹, Larry A Allen², Christopher S Lee³, Quin E Denfeld⁴, Josef Stehlik⁵, David Cella⁶, Joann Lindenfeld⁷, Jeffrey J Teuteberg⁸, Colleen K McIlvennan², Michael S Kiernan⁹, David G Beiser¹⁰, Mary N Walsh¹¹, Eric D Adler¹², Bernice Ruo¹², James K Kirklin¹³, Liviu Klein¹⁴, Katy Bedjeti⁶, Peter D Cummings⁶, James L Burns⁶, Alyssa M Vela¹⁵, Kathleen L Grady¹⁵

Affiliations

¹ Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL. Electronic address: e-hahn@northwestern.edu.
² Department of Cardiology, University of Colorado, Aurora, CO.
³ Boston College William F. Connell School of Nursing, Chestnut Hill, MA.
⁴ Oregon Health & Science University School of Nursing, Portland, OR.
⁵ Department of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, UT.
⁶ Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL.
⁷ Department of Medicine, Vanderbilt University, Nashville, TN.
⁸ Falk Cardiovascular Institute, Stanford University, Stanford, CA.
⁹ Department of Medicine, Tufts Medical Center, Boston, MA.
¹⁰ Department of Medicine, University of Chicago, Chicago, IL.
¹¹ Ascension St. Vincent Heart Center, Indianapolis, IN.
¹² Department of Medicine, University of California, San Diego, CA.
¹³ Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
¹⁴ Department of Medicine, University of California, San Francisco, CA.
¹⁵ Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL.

Abstract

Study participants (n = 272) completed 12 Patient-Reported Outcomes Measurement Information System (PROMIS) physical, mental and social health measures (questionnaires) prior to implantation of a left ventricular assist device (LVAD) and again at 3 and 6 months postimplant. All but 1 PROMIS measure demonstrated significant improvement from pre-implant to 3 months; there was little change between 3 and 6 months. Because PROMIS measures were developed in the general population, patients with an LVAD, their caregivers and their clinicians can interpret the meaning of PROMIS scores in relation to the general population, helping them to monitor a return to normalcy in everyday life.

Keywords: Heart failure; left ventricular assist device; longitudinal study; patient-reported outcomes.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Adaptation, Psychological
Adult
Aged
Female
Follow-Up Studies
Health Status
Heart Failure* / psychology
Heart Failure* / surgery
Heart Failure* / therapy
Heart-Assist Devices* / psychology
Humans
Male
Mental Health*
Middle Aged
Patient Reported Outcome Measures
Quality of Life* / psychology
Surveys and Questionnaires
Time Factors
Treatment Outcome

Grants and funding

R01 HL130502/HL/NHLBI NIH HHS/United States