Protocol letter: Intra-treatment Image Guided Adaptive Radiotherapy Dose-escalation Study (InGReS) - A Phase 1 multicentre feasibility study

Delali Adjogatse; Andriana Michaelidou; Beatriz Sanchez Nieto; Robert Kozarski; Isabel Sassoon; Mererid Evans; Thomas Rackley; Simon Shah; David Eaton; Lucy Pike; Sorcha Curry; Sarah-May Gould; Christopher Thomas; Anthony Kong; Imran Petkar; Miguel Reis-Ferreira; Stephen Connor; Sally Fiona Barrington; Mary Lei; Teresa Guerrero Urbano

doi:10.1016/j.radonc.2023.109645

Protocol letter: Intra-treatment Image Guided Adaptive Radiotherapy Dose-escalation Study (InGReS) - A Phase 1 multicentre feasibility study

Radiother Oncol. 2023 Jun:183:109645. doi: 10.1016/j.radonc.2023.109645. Epub 2023 Mar 28.

Authors

Delali Adjogatse¹, Andriana Michaelidou², Beatriz Sanchez Nieto³, Robert Kozarski⁴, Isabel Sassoon⁵, Mererid Evans⁶, Thomas Rackley⁶, Simon Shah⁷, David Eaton⁸, Lucy Pike⁴, Sorcha Curry⁹, Sarah-May Gould⁹, Christopher Thomas⁸, Anthony Kong¹⁰, Imran Petkar¹⁰, Miguel Reis-Ferreira¹⁰, Stephen Connor¹¹, Sally Fiona Barrington¹², Mary Lei¹⁰, Teresa Guerrero Urbano¹³

Affiliations

¹ School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; Department of Clinical Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK. Electronic address: Delali.adjogatse@gstt.nhs.uk.
² School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; Department of Clinical Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
³ Institute of Physics, Pontificia Universidad Catolica de Chile, Santiago, Chile.
⁴ School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK.
⁵ Computer Science Department, Brunel University London, Uxbridge, UK.
⁶ Department of Oncology, Velindre University NHS Trust, Cardiff, UK.
⁷ Department of Medical Physics, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁸ School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; Department of Medical Physics, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁹ King's College and Guy's and St Thomas' Hospital PET Centre, London, UK.
¹⁰ Department of Clinical Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
¹¹ School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; Department of Radiology Guy's and St Thomas' NHS Foundation Trust, London, UK; Department of Neuroradiology, King's College Hospital, London UK.
¹² School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK; King's College and Guy's and St Thomas' Hospital PET Centre, London, UK.
¹³ Department of Clinical Oncology, Guy's and St Thomas' NHS Foundation Trust, London, UK; King's College London, Faculty of Dentistry, Oral and Craniofacial Sciences, London, UK.

PMID: 36997123
DOI: 10.1016/j.radonc.2023.109645

No abstract available

Publication types

Clinical Trial Protocol
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Clinical Trials, Phase I as Topic
Feasibility Studies
Humans
Multicenter Studies as Topic
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted / methods
Radiotherapy, Image-Guided* / methods
Radiotherapy, Intensity-Modulated* / methods

Grants and funding

203148/Z/16/Z/WT_/Wellcome Trust/United Kingdom