Food additive succinate exacerbates experimental autoimmune encephalomyelitis accompanied by increased IL-1β production

Affiliations

• ¹ Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
• ² Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. Electronic address: mkinoshita@neurol.med.osaka-u.ac.jp.
• ³ Genome Information Research Center, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan.
• ⁴ Japan Community Health Care Organization Osaka Hospital, Osaka, Osaka, Japan.
• ⁵ Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; Department of Neurology, Suita Municipal Hospital, Suita, Osaka, Japan.
• ⁶ Department of Immunology and Genomics, Osaka Metropolitan University, Graduate School of Medicine, Osaka, Osaka, Japan; Division of Metagenome Medicine, Human Genome Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Division of Innate Immune Regulation, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
• ⁷ Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Suita, Osaka, Japan.
• ⁸ Department of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan. Electronic address: okuno@neurol.med.osaka-u.ac.jp.