Screening for Vocal Fold Movement Impairment in Children Undergoing Esophageal and Airway Surgery

Laryngoscope. 2023 Dec;133(12):3564-3570. doi: 10.1002/lary.30646. Epub 2023 Mar 9.

Abstract

Introduction: Children undergoing cervical and/or thoracic operations are at risk for recurrent laryngeal nerve injury, resulting in vocal fold movement impairment (VFMI). Screening for VFMI is often reserved for symptomatic patients.

Objective: Identify the prevalence of VFMI in screened preoperative patients prior to an at-risk operation to evaluate the value of screening all patients at-risk for VFMI, regardless of symptoms.

Methods: A single center, retrospective review of all patients undergoing a preoperative flexible nasolaryngoscopy between 2017 and 2021, examining the presence of VFMI and associated symptoms.

Results: We evaluated 297 patients with a median (IQR) age of 18 (7.8, 56.3) months and a weight of 11.3 (7.8, 17.7) kilograms. Most had a history of esophageal atresia (EA, 60%), and a prior at-risk cervical or thoracic operation (73%). Overall, 72 (24%) patients presented with VFMI (51% left, 26% right, and 22% bilateral). Of patients with VFMI, 47% did not exhibit the classic symptoms (stridor, dysphonia, and aspiration) of VFMI. Dysphonia was the most prevalent classic VFMI symptom, yet only present in 18 (25%) patients. Patients presenting with a history of at-risk surgery (OR 2.3, 95%CI 1.1, 4.8, p = 0.03), presence of a tracheostomy (OR 3.1, 95%CI 1.0, 10.0, p = 0.04), or presence of a surgical feeding tube (OR 3.1, 95%CI 1.6, 6.2, p = 0.001) were more likely to present with VFMI.

Conclusion: Routine screening for VFMI should be considered in all at-risk patients, regardless of symptoms or prior operations, particularly in those with a history of an at-risk surgery, presence of tracheostomy, or a surgical feeding tube.

Level of evidence: 3 Laryngoscope, 133:3564-3570, 2023.

Keywords: EA; RLN; VFMI; esophageal atresia; prevalence; recurrent laryngeal nerve injury; screening; vocal fold movement impairment.

MeSH terms

  • Child
  • Dysphonia* / diagnosis
  • Dysphonia* / epidemiology
  • Dysphonia* / etiology
  • Humans
  • Infant
  • Postoperative Complications / epidemiology
  • Retrospective Studies
  • Vocal Cord Paralysis* / diagnosis
  • Vocal Cord Paralysis* / epidemiology
  • Vocal Cord Paralysis* / etiology
  • Vocal Cords / injuries