Transition Metal-Catalyzed C-H Functionalization Through Electrocatalysis

Abstract

Electrochemically promoted transition metal-catalyzed C-H functionalization has emerged as a promising area of research over the last few decades. However, development in this field is still at an early stage compared to traditional functionalization reactions using chemical-based oxidizing agents. Recent reports have shown increased attention on electrochemically promoted metal-catalyzed C-H functionalization. From the standpoint of sustainability, environmental friendliness, and cost effectiveness, electrochemically promoted oxidation of a metal catalyst offers a mild, efficient, and atom-economical alternative to traditional chemical oxidants. This Review discusses advances in the field of transition metal-electrocatalyzed C-H functionalization over the past decade and describes how the unique features of electricity enable metal-catalyzed C-H functionalization in an economic and sustainable way.

Keywords: C−H functionalization; electrochemistry; electrosynthesis; homogeneous catalysis; transition metals.