Cutaneous Sporothrix globosa infection mimicking cryptococcosis in a patient with history of kidney transplant

J Cutan Pathol. 2023 Jul;50(7):629-631. doi: 10.1111/cup.14396. Epub 2023 Feb 15.

Abstract

Sporotrichosis is a subacute-to-chronic infection caused by Sporothrix species, a dimorphic fungus. Virulence varies by Sporothrix species and presentation can be region dependent. The patient had a history of immunosuppression as a result of a kidney transplant, and presented with a high disease burden on histopathological examination, but responded well to itraconazole. The case suggests considering Sporothrix speciation in immunocompromised patients to best determine treatment modality and duration.

Keywords: Sporothrix; fungal infection; sporotrichosis; transplant.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Cryptococcosis*
  • Humans
  • Itraconazole
  • Kidney Transplantation*
  • Sporothrix*
  • Sporotrichosis* / diagnosis
  • Sporotrichosis* / microbiology
  • Sporotrichosis* / pathology

Substances

  • Itraconazole
  • Antifungal Agents

Supplementary concepts

  • Sporothrix globosa