[The "epileptogenic zone" in humans: representation of intercritical events by spatio-temporal maps]

Rev Neurol (Paris). 1987;143(5):443-50.
[Article in French]

Abstract

In the preoperative investigation of partial epilepsies, electrical characteristics of the so-called epileptogenic area are of critical interest to localize this area. We have always emphasized that the analysis of ictal events themselves, is more valuable than that of inter-ictal anomalis. One reason for this emphasis has been the absence of a reliable method to evaluate the relationship between the topography of ictal and interictal events. An technique for imaging an intracerebral potential field is reported. It allows to analyse the spatio-temporal distribution of interictal events recorded during the SEEG exploration. This technique applied to an illustrative patient shows that the temporo-spatial distribution of interictal spikes is related to that of the ictal discharge itself. A new hypothesis concerning the build up of an epileptogenic area in man is presented.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Brain Mapping*
  • Electroencephalography
  • Epilepsy / pathology
  • Epilepsy / physiopathology*
  • Frontal Lobe / pathology
  • Frontal Lobe / physiopathology*
  • Humans
  • Male
  • Temporal Lobe / pathology
  • Temporal Lobe / physiopathology*