Homicidal ideation and psychiatric comorbidities in the inpatient adolescents aged 12-17

Ching-Fang Sun; Zeeshan Mansuri; Chintan Trivedi; Ramu Vadukapuram; Abhishek Reddy

doi:10.3389/fpsyt.2022.933524

Homicidal ideation and psychiatric comorbidities in the inpatient adolescents aged 12-17

Front Psychiatry. 2022 Nov 16:13:933524. doi: 10.3389/fpsyt.2022.933524. eCollection 2022.

Authors

Ching-Fang Sun¹, Zeeshan Mansuri², Chintan Trivedi³, Ramu Vadukapuram⁴, Abhishek Reddy¹

Affiliations

¹ Department of Psychiatry, Virginia Tech Carilion School of Medicine, Roanoke, VA, United States.
² Department of Psychiatry, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States.
³ Department of Psychiatry, Texas Tech University Health Science Center at Permian Basin, Odessa, TX, United States.
⁴ Department of Psychiatry, The University of Texas Rio Grande Valley, Harlingen, TX, United States.

Abstract

Objectives: Adolescents with a homicidal tendency is a growing concern in the United States. Studies in the past have showcased the relationship between homicidal ideation (HI) and psychiatric illnesses, but very limited information is available on the adolescent and inpatient population. We aim to evaluate the prevalence of demographic characteristics and psychiatric disorders in adolescents with and without HI.

Materials and methods: Adolescent (age 12-17) population admitted to the hospital with the diagnosis of homicidal ideation was identified from the 2016-2018 National Inpatient Sample Dataset (NISD). Patients without HI were defined as the control group. The prevalence of psychiatric comorbidities between the groups was compared by applying the Rao-Scott adjusted chi-square test. We used multivariable logistic regression to generate odds ratio (OR) of homicidal ideation as an outcome; we adjusted age, sex, race, socioeconomic status, substance use disorders, alcohol use disorders, and psychiatric comorbidities.

Results: A total of 18,935 patients (mean age: 14.5) with HI diagnosis were identified in this study. Majority of the patients were male subjects in the HI group compared to the control group (58.7 vs. 41.2%, p < 0.001). Racially, HI was more prevalent in white race (56.0 vs. 52.6%, p < 0.001) and black race (22.3 vs. 17.8%, p < 0.001), compared to Hispanic race (14.9 vs. 21.3%, p < 0.001). Major depression (Odds ratio [OR]: 2.66, p < 0.001), bipolar disorder (OR: 3.52, p < 0.001), anxiety disorder (OR: 1.85, p < 0.001), ADHD, and other conduct disorders (OR: 4.01, p < 0.001), schizophrenia (OR: 4.35, p < 0.001) are strong predictors of HI. Suicidality was prevalent in 66.9% of patients with HI.

Conclusion: We found a higher prevalence of psychiatric illnesses such as depression, anxiety, and bipolar disorder in adolescents with homicidal ideation in the inpatient setting. White and black races were more prevalent in patients with homicidal ideation. Further large-scale longitudinal research studies are warranted to establish the correlation between psychiatric disorders and homicidal ideation among adolescents.

Keywords: adolescents; anxiety; bipolar disorder; depression; homicide; psychiatric comorbidity.