Symptom evolution in the dying

BMJ Support Palliat Care. 2023 Mar;13(1):121-124. doi: 10.1136/spcare-2022-003718. Epub 2022 Nov 21.

Abstract

Objective: Provide insight in the prevalence of symptoms in patients who are in the last days of life.

Methods: A retrospective descriptive analysis of data on patients who died between 2012 and 2019 at the age of 18 or older in 1 of 20 Dutch healthcare facilities, including hospitals, inpatient hospices and long-term care facilities. We analysed data from 4 hourly registrations in the Care Programme for the Dying Person, to assess for how many patients symptom-related goals of care were not achieved. We looked at the first 4 hours episode after the start of the Care Programme and the last 4 hours episode prior to death.

Results: We analysed records of 2786 patients. In the first 4 hours episode, at least one symptom-related care goal was not achieved for 28.5%-42.8% of patients, depending on the care setting. In the last 4 hours episode, these percentages were 17.5%-26.9%. Care goals concerning pain and restlessness were most often not achieved: percentages varied from 7.3% to 20.9% for pain and from 9.3% to 21.9% for restlessness.

Conclusions: Symptom control at the end of life is not optimal in a substantial minority of patients. Systematic assessment and attention as well as further research on symptom management are of the essence.

Keywords: End of life care; Terminal care.

MeSH terms

  • Humans
  • Pain
  • Palliative Care
  • Psychomotor Agitation
  • Retrospective Studies
  • Terminal Care*