We applied a new serosurveillance tool to estimate typhoidal Salmonella burden using samples collected during 2020 from a population in Juba, South Sudan. By using dried blood spot testing, we found an enteric fever seroincidence rate of 30/100 person-years and cumulative incidence of 74% over a 4-year period.
Keywords: Juba; Paratyphi; Salmonella enterica; South Sudan; Typhi; bacteria; enteric fever; enteric infections; salmonella; typhoidal salmonella.