3D figure of epilepsy syndromes

Rima Nabbout; Mathieu Kuchenbuch; Paolo Tinuper; J Helen Cross; Elaine Wirrell

doi:10.1002/epi4.12665

3D figure of epilepsy syndromes

Epilepsia Open. 2023 Mar;8(1):217-220. doi: 10.1002/epi4.12665. Epub 2022 Nov 10.

Authors

Rima Nabbout^{1

2}, Mathieu Kuchenbuch^{3

4}, Paolo Tinuper^{5

6}, J Helen Cross⁷, Elaine Wirrell⁸

Affiliations

¹ Reference Center for Rare Epilepsies, Department of Pediatric Neurology, Necker-Enfants Malades Hospital, APHP, member of EpiCARE, University Paris cité, Paris, France.
² Imagine Institute, National Institute of Health and Medical Research, Mixed Unit of Research, INSERM, Paris, France.
³ Department of Pediatric Neurology, University Hospital of Nancy, member of EpiCARE, Lorraine University, Nancy, France.
⁴ Research Center for Automatic Control of Nancy (CRAN), Lorraine University, CNRS, UMR, Vandoeuvre, France.
⁵ Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
⁶ Institute of Neurological Sciences, member of EpiCARE, Scientific Institute for Research and Health Care, Bologna, Italy.
⁷ Programme of Developmental Neurosciences, University College London National Institute for Health Research Biomedical Research Centre Great Ormond Street Institute of Child Health, Great Ormond Street Hospital for Children, and Young Epilepsy Lingfield, London, UK.
⁸ Divisions of Child and Adolescent Neurology and Epilepsy, Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.

Abstract

We propose an instructive figure that summarized the classification of epilepsy syndromes according to the 2022 report of the ILAE Task Force on Nosology and Definitions. Our aim is to present on the same figure different concepts such as the names of epilepsy syndromes, their extreme and classical ages of onset, their epilepsy types (generalized, focal, or generalized and focal) but also their membership in groups of epilepsy syndromes as for self-limited or developmental and epileptic encephalopathies. With this figure, we provide an interactive tool, as supplementary data, helping to present this classification and link it to electro-clinical mandatory, alerts, and exclusionary criteria of each syndrome, in accordance with the ILAE position papers on syndromes classification and nosology. This report may be used as an illustrative tool for teaching epilepsy syndromes and as a practical and comprehensive aid for the classification of epilepsy individuals' syndromes.

Keywords: developmental and epileptic encephalopathy; epilepsy syndromes; interactive classification; self-limited epilepsies; teaching tool.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Advisory Committees
Epilepsy*
Epilepsy, Generalized*
Epileptic Syndromes*
Humans