Finding pleasure in repetitive behaviors

Ying Zhang; Dheeraj S Roy; Guoping Feng

doi:10.1016/j.neuron.2022.09.022

Finding pleasure in repetitive behaviors

Neuron. 2022 Oct 19;110(20):3225-3227. doi: 10.1016/j.neuron.2022.09.022.

Authors

Ying Zhang¹, Dheeraj S Roy², Guoping Feng³

Affiliations

¹ McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA.
² Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
³ McGovern Institute for Brain Research, Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA, USA; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: fengg@mit.edu.

PMID: 36265440
DOI: 10.1016/j.neuron.2022.09.022

Abstract

In this issue of Neuron, Sun et al. (2022) identify a neuronal subpopulation in the medial paralemniscal nucleus that underlies repetitive self-grooming. Through their projections to dopamine neurons in the ventral tegmental area, this subpopulation also drives reward and alleviates anxiety.

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MeSH terms

Animals
Dopaminergic Neurons / physiology
Pleasure*
Reward
Ventral Tegmental Area* / physiology