Molecular detection and identification of relapsing fever Borrelia in ticks and wild small mammals in China

Emerg Microbes Infect. 2022 Dec;11(1):2632-2635. doi: 10.1080/22221751.2022.2134054.

Abstract

We identified relapsing fever (RF) Borrelia in 1.45% (145/10426) of the ticks and 1.40% (40/2850) of the wild mammals in a field investigation in China. Three RF Borrelia species, including human-pathogenic Borrelia miyamotoi, Borrelia persica and unclassified Babesia sp. were determined. Main species determined from ticks was B. miyamotoi (44.14%), followed by the unclassified Borrelia sp. (42.76%), and Borrelia theileri (13.10%). In wild mammals, main species found was B. persica (57.50%), followed by the unclassified Borrelia sp. (40.00%), and B. miyamotoi (2.50%). We determined B. theileri and B. persica in China for the first time. The coexistence of RF Borrelia species in one tick species in a given region was observed, with the most frequent coexistence seen for B. miyamotoi and the unclassified Borrelia sp. in Dermacentor silvarum, Haemaphysalis japonica, Haemaphysalis longicornis, and Ixodes persulcatuss respectively. The wide distribution and high variety of RF Borrelia in China pose a potential threat to public health.

Keywords: Borrelia; China; Relapsing fever; mammal; tick.

Publication types

  • Letter

MeSH terms

  • Animals
  • Borrelia* / genetics
  • China / epidemiology
  • Humans
  • Ixodes*
  • Ixodidae*
  • Mammals
  • Relapsing Fever* / diagnosis
  • Relapsing Fever* / epidemiology
  • Relapsing Fever* / veterinary

Grants and funding

This work was supported by National Natural Science Foundation of China [grant number 81825019, 81621005].